| S Curves | section of N.C. Highway 12 N of Rodanthe on Hatteras Island, E Dare County. Term adopted by N.C. Department of Transportation because of frequent need to repair damage due to washouts. Also called Rodanthe S Curves. |
| Sa-koh-na-gas | See Blue Ridge Mountains. |
| Saconon | community in E Henderson County on Little Hungry Creek served by post office, 1913-23. |
| Saddle Gap | N Transylvania County between Looking Glass Creek and Avery Creek. |
| Saddle Mountain | on the Alleghany-Surry county line. |
| Saddle Mountain Creek | rises in W Surry County and flows SE into Mitchell River. |
| Saddle Tree Gap | W Graham County between the headwaters of Hangover Creek and Deep Creek. |
| Saddleback | ridge in NW Swain County in Great Smoky Mountains National Park between Roaring Creek and Desolation Branch. Its center is near lat. 35°33'26" N., long. 83°40'48" W. |
| Saddletree Swamp | rises in N Robeson County and flows S into Lumber River. |
| Saddletree Township | central Robeson County. |