| Lowery Creek | rises in S Macon County between Devils Prong and Little Indian Creek. |
| Lowery Knob | central Macon County between Dobson Branch and Salser Branch. |
| Lowery Mill Creek | rises in N central Forsyth County and flows S and SW into Salem Lake. |
| Lowes Grove | community in S Durham County on W edge of Research Triangle Park. |
| Lowesville | community in SE Lincoln County. Named for Lowe family. |
| Lowgap | community in NW Surry County. Named for a nearby low gap in the Blue Ridge Mountains. |
| Lowing Bald | SW Swain County near the head of Big Creek. |
| Lowland | community on W Goose Creek Island, NE Pamlico County. Post office est. 1892. Processes seafood. |
| Loy | community in S Alamance County served by post office, 1879-1905. Known as Loy's Shop until 1895. |
| Loy's Store | See Loy. |