| Deep Run | rises in SW Lenoir County and flows NE into Southwest Creek. |
| Deep Run | a stream fed by several canals in E Beaufort County, flows W into Broad Creek. |
| Deep Run Swamp | rises in E Martin County and flows NW into Gardners Creek. |
| Deep Swamp Branch | rises in SE Hertford County and flows NE into Chowan River. |
| Deep Water Point | appears on the Moseley map, 1733, in what is now Brunswick County between Elizabeth River and Walden Creek, E of the present town of Southport. Appeared as late as 1851-53 on navigation charts. See also Walkersburg. |
| Deeplow Gap | N Swain County on the E slope of Thomas Ridge in Great Smoky Mountains National Park. |
| Deer Branch | rises in N Yancey County and flows SE into Big Branch. |
| Deer Branch | rises in NE Franklin County and flows E into Sandy Creek. |
| Deer Creek | rises in NW Haywood County and flows SE into Big Creek. |
| Deer Creek | rises in SW Carteret County and flows S 2 mi. into Bogue Sound. |